Guidelines for Canadian Drinking Water Quality: Guideline Technical Document – 1,2–Dichloroethane

Table of Contents

• Part I. Overview and Application
  • 1.0 Guideline
  • 2.0 Executive summary
    • 2.1 Health effects
    • 2.2 Exposure
    • 2.3 Analysis and treatment
    • 3.0 Application of the guideline
    • Part II. Science and Technical Considerations
      • 4.0 Identity, uses, sources and fate in the environment
        • 4.1 Identity
        • 4.2 Major uses and sources
        • 4.3 Environmental fate
      • 5.0 Exposure
        • 5.1 Water
        • 5.2 Food
        • 5.3 Air
        • 5.4 Consumer products
        • 5.5 Soil
        • 5.6 Multi-route exposure through drinking water
        • 5.6.1 Dermal exposure
        • 5.6.2 Inhalation exposure
        • 5.6.3 PBPK approach for multiroute exposure assessment
        • 5.6.4 Conclusion for multiroute exposure assessment
      • 6.0 Analytical methods
      • 7.0 Treatment technology
        • 7.1 Municipal scale
          • 7.1.1 Activated carbon adsorption
          • 7.1.2 Air stripping: packed tower aeration
          • 7.1.3 Combination of aeration and granular activated carbon
          • 7.1.4 Membrane filtration
          • 7.1.5 Advanced oxidation processes
          • 7.1.6 Emerging treatment technologies
          • 7.2 Residential scale
      • 8.0 Kinetics and metabolism
        • 8.1 Absorption
        • 8.2 Distribution
          • 8.2.1 Humans
          • 8.2.2 Experimental animals
        • 8.3 Metabolism
          • 8.3.1 Humans
          • 8.3.2 Experimental animals
        • 8.4 Excretion
        • 8.5 Physiologically based pharmacokinetic (PBPK) modelling
      • 9.0 Health effects
        • 9.1 Effects in humans
          • 9.1.1 Acute toxicity
          • 9.1.2 Subchronic and chronic toxicity
          • 9.1.3 Carcinogenicity
          • 9.1.4 Genotoxicity
          • 9.1.4.1 In vitro
          • 9.1.4.2 In vivo
          • 9.1.5 Reproductive and developmental toxicity
        • 9.2 Effects on experimental animals
          • 9.2.1 Acute toxicity
          • 9.2.2 Short-term exposure
          • 9.2.3 Long-term exposure and carcinogenicity
          • 9.2.4 Genotoxicity
            • 9.2.4.1 In vitro
            • 9.2.4.2 In vivo
          • 9.2.5 Reproductive and developmental toxicity
            • 9.2.5.1 Developmental effects
            • 9.2.5.2 Reproductive effects
          • 9.2.6 Mode of action
        • 10.0 Classification and assessment
          • 10.1 Cancer risk assessment
          • 10.2 Non-cancer risk assessment
          • 10.3 Comparison of cancer and non-cancer risk assessments
          • 10.4 International considerations
        • 11.0 Rationale
        • 12.0 References
      • Appendix A: List of acronyms